Sermorelin
$119/moon the monthly plan
Sermorelin is a lab-made version of a signal the brain naturally sends. It prompts the pituitary—a small gland at the base of the brain—to release growth hormone. Halwel offers it as a compounded under-the-skin injection with clinician review and follow-up. Benefits for sleep, muscle, body fat, energy, or longevity have not been proven for this use.
One price, everything included
$119/mo
$119 charged once your prescription is approved
Check your eligibilityA licensed provider reviews every intake before treatment is prescribed.
FormulationSermorelin 10mg
How Sermorelin works
We would rather you understand the medicine than take our word for it.
It copies a signal your brain already makes
The brain normally makes growth hormone-releasing hormone, or GHRH. GHRH tells the pituitary gland to release growth hormone. Sermorelin is a short, lab-made version of that signal. It does not contain growth hormone itself.
It asks the pituitary to release growth hormone
If the pituitary gland can respond, sermorelin may increase the amount of growth hormone it releases. The response can vary with age, sleep, body composition, other hormones, dose, and the health of the pituitary gland.
Corpas et al., Journal of Clinical Endocrinology & Metabolism, 1992
Another hormone, IGF-1, may rise
Growth hormone tells the liver and other tissues to make insulin-like growth factor 1, or IGF-1. IGF-1 is a hormone that carries out some of growth hormone’s effects on cells and tissues. Because growth hormone rises and falls throughout the day, clinicians may use an IGF-1 blood test as one clue about growth-hormone activity. A higher result is not automatically better and does not prove better strength, sleep, thinking, or lifespan.
Thoughtful care in four clear steps
Medical intake
Tell us about your health history, current medications, goals, and prior treatment. This is a medical screening, not a product order.
Clinical review
A licensed clinician in your state independently decides whether treatment is appropriate. A prescription is not guaranteed.
Medication delivery
If prescribed, a licensed pharmacy prepares your medication and ships it in discreet packaging. Compounded medications are not FDA-approved.
Ongoing care
Use your portal for check-ins, dose questions, side effects, refills, and treatment changes. Your clinician can adjust or stop treatment based on your health and response.
What changes
The outcomes measured in trials, each with its source.
Hormone levels can rise
In a small study of ten healthy older men, 14 days of higher-dose GHRH injections raised growth hormone and IGF-1 levels. The study showed that the hormone system responded. It did not show that the men felt better, functioned better, or lived longer.
What to keep in mind: It did not show that the men felt better, functioned better, or lived longer.
Corpas et al., 1992Small studies measured body changes
In a three-month study of 22 healthy middle-aged and older men, higher-dose GHRH raised growth hormone and IGF-1. Researchers also measured more body water and non-fat body mass, less abdominal fat, and changes in some physical tests. Skin reactions occurred where the medicine was injected. This was a small study of a different form of GHRH—not a large trial of Halwel’s compounded sermorelin.
What to keep in mind: This was a small study of a different form of GHRH—not a large trial of Halwel’s compounded sermorelin.
Veldhuis et al., Journal of Clinical Endocrinology & Metabolism, 2004Longevity is not established
No clinical trial has shown that compounded sermorelin extends life, prevents age-related disease, or restores youth. Knowing how a hormone pathway works is not the same as proving a health benefit.
What to keep in mind: Knowing how a hormone pathway works is not the same as proving a health benefit.
These symptoms can have many causes
Low energy, poor sleep, reduced strength, changes in muscle or body fat, and feeling unwell can have many causes. These symptoms do not prove that growth-hormone activity is low. A clinician should look for more established causes before prescribing.
What to keep in mind: A clinician should look for more established causes before prescribing.
Sermorelin questions
What patients ask most before starting. If yours isn't here, your clinician answers it during review.
Halwel offers a one-month plan for compounded sermorelin, supplied as an under-the-skin injection if a clinician prescribes it. Sermorelin is a lab-made copy of part of the brain’s natural “release growth hormone” signal. It asks your pituitary gland to release your own growth hormone; it is not an injection of growth hormone.
No. Sermorelin was previously FDA-approved for use in certain children whose bodies did not make enough growth hormone. This compounded adult healthy-aging use is not FDA-approved. FDA has not reviewed this compounded product for safety, effectiveness, or quality.
IGF-1 stands for insulin-like growth factor 1. It is a hormone, made mainly by the liver, that carries out some of growth hormone’s effects on cells and tissues. Its blood level is steadier than growth hormone’s, so clinicians may use it as one clue about growth-hormone activity. Sermorelin may raise IGF-1, but a higher number does not prove better energy, sleep, strength, muscle, body fat, or longevity.
Those results have not been proven for this compounded use. Small studies of the brain’s growth-hormone signal measured hormone levels and changes in muscle, fat, and body water. They were too small and too different from this product to predict who will feel or function better.
Testing depends on your symptom, goal, and health history. The clinician may check IGF-1, thyroid function, blood sugar, or other hormones. No single blood-test result can determine whether treatment is appropriate or working.
Follow the pharmacy label for mixing the medicine, measuring the dose, timing the under-the-skin injection, storing the vial, and knowing when it expires. Products can differ, so never copy instructions from another vial or an online dosing plan.
Watch for injection-site reactions, flushing, headache, dizziness, nausea, swelling, joint symptoms, numbness or tingling, or changes in blood sugar. Report unexpected symptoms rather than assuming they are part of the process.
Treatment should stop or change for a concerning reaction, an unsafe vial or injection problem, or a concerning blood-test result. It should also change if there is no meaningful benefit by the agreed review date or a new health concern appears.
The one-month plan includes one 10 mg vial of compounded sermorelin if prescribed, clinician review, follow-up support, and shipping. There is no separate membership fee.
When you’re ready, begin with a short medical intake.
A licensed clinician will review your health and decide whether treatment is appropriate.